RRC ID 41574
著者 Han SY, Hu Y, Anno T, Yanagita T.
タイトル S-propyl cysteine reduces the secretion of apolipoprotein B100 and triacylglycerol by HepG2 cells.
ジャーナル Nutrition
Abstract A number of sulfur-containing amino acids and peptides are found in allium plants such as onion and garlic that have physiologic functions. In HepG2 cells, S-propyl cysteine decreased the secretion of apolipoprotein B100. The compound reduced the secretion of newly synthesized triacylglycerol and cholesterols from radiolabeled acetate. We associated the decrease of apolipoprotein B100 secretion to the length of the acyl-chain of the sulfur-containing amino acids. The present study suggests that foods containing S-propyl cysteine including onions have beneficial effects.
巻・号 18(6)
ページ 505-9
公開日 2002-6-1
DOI 10.1016/s0899-9007(02)00749-9
PII S0899900702007499
PMID 12044824
MeSH Allium / chemistry* Apolipoprotein B-100 Apolipoproteins B / drug effects* Apolipoproteins B / metabolism Cholesterol / metabolism Culture Media Cysteine / analogs & derivatives* Cysteine / pharmacology* Humans Kinetics Plant Extracts / pharmacology Triglycerides / metabolism* Tumor Cells, Cultured
IF 3.639
引用数 10
WOS 分野 NUTRITION & DIETETICS
リソース情報
ヒト・動物細胞