論文 - 詳細
RRC ID | 41574 |
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著者 | Han SY, Hu Y, Anno T, Yanagita T. |
タイトル | S-propyl cysteine reduces the secretion of apolipoprotein B100 and triacylglycerol by HepG2 cells. |
ジャーナル | Nutrition |
Abstract |
A number of sulfur-containing amino acids and peptides are found in allium plants such as onion and garlic that have physiologic functions. In HepG2 cells, S-propyl cysteine decreased the secretion of apolipoprotein B100. The compound reduced the secretion of newly synthesized triacylglycerol and cholesterols from radiolabeled acetate. We associated the decrease of apolipoprotein B100 secretion to the length of the acyl-chain of the sulfur-containing amino acids. The present study suggests that foods containing S-propyl cysteine including onions have beneficial effects. |
巻・号 | 18(6) |
ページ | 505-9 |
公開日 | 2002-6-1 |
DOI | 10.1016/s0899-9007(02)00749-9 |
PII | S0899900702007499 |
PMID | 12044824 |
MeSH | Allium / chemistry* Apolipoprotein B-100 Apolipoproteins B / drug effects* Apolipoproteins B / metabolism Cholesterol / metabolism Culture Media Cysteine / analogs & derivatives* Cysteine / pharmacology* Humans Kinetics Plant Extracts / pharmacology Triglycerides / metabolism* Tumor Cells, Cultured |
IF | 3.639 |
引用数 | 10 |
WOS 分野 | NUTRITION & DIETETICS |
リソース情報 | |
ヒト・動物細胞 |