RRC ID 42076
Author Guo H, Koike K, Li W, Satou T, Guo D, Nikaido T.
Title Saponins from the flower buds of Buddleja officinalis.
Journal J Nat Prod
Abstract Five new saponins, mimengosides C-G (1-5), were isolated from the flower buds of Buddleja officinalis along with five known compounds, namely, songaroside A, acteoside, phenylethyl 2-glucoside, echinacoside, and phenylethyl alcohol 8-O-beta-D-glucopyranosyl-(1-->2)-beta-D-glucopyranoside. The structures of 1-5 were elucidated using spectroscopic and chemical methods, and these compounds were evaluated for their inhibitory effects against HL-60 leukemia cells.
Volume 67(1)
Pages 10-3
Published 2004-1-1
DOI 10.1021/np0300131
PMID 14738377
MeSH Buddleja / chemistry* Cell Line, Tumor Drug Screening Assays, Antitumor Drugs, Chinese Herbal / chemistry Drugs, Chinese Herbal / isolation & purification* Drugs, Chinese Herbal / pharmacology Flowers / chemistry Humans Molecular Structure Nuclear Magnetic Resonance, Biomolecular Plants, Medicinal / chemistry* Saponins / chemistry Saponins / isolation & purification* Saponins / pharmacology Stereoisomerism
IF 3.782
Times Cited 27
WOS Category PHARMACOLOGY & PHARMACY PLANT SCIENCES CHEMISTRY, MEDICINAL
Resource
Human and Animal Cells