| RRC ID |
42261
|
| Author |
Yamada M, Matsuura N, Suzuki H, Kurosaka C, Hasegawa N, Ubukata M, Tanaka T, Iinuma M.
|
| Title |
Germacranolides from Calea urticifolia.
|
| Journal |
Phytochemistry
|
| Abstract |
Four germacranolides, named calealactones A-C and calealactone B [corrected] were isolated from the leaves of Calea urticifolia (Compositae) in addition to three known germacranolides. Their structures were established on the basis of spectroscopic analysis including by 2D NMR spectroscopy. Calealactone C and 2,3-epoxyjuanisulamin displayed potent toxicity to U937 cells.
|
| Volume |
65(23)
|
| Pages |
3107-11
|
| Published |
2004-12-1
|
| DOI |
10.1016/j.phytochem.2004.08.040
|
| PII |
S0031-9422(04)00424-8
|
| PMID |
15541738
|
| MeSH |
Antineoplastic Agents, Phytogenic / isolation & purification
Antineoplastic Agents, Phytogenic / pharmacology
Asteraceae / chemistry*
Humans
Leukemia
Magnetic Resonance Spectroscopy
Molecular Structure
Plant Leaves / chemistry
Sesquiterpenes, Germacrane / chemistry*
Sesquiterpenes, Germacrane / isolation & purification
Sesquiterpenes, Germacrane / pharmacology
U937 Cells
|
| IF |
3.044
|
| Times Cited |
25
|
|
WOS Category
|
PLANT SCIENCES
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
| Resource |
| Human and Animal Cells |
U-937 DE-4(RCB0435) |
