Reference - Detail
| RRC ID | 42430 |
|---|---|
| Author | Oka T, Hansman GS, Katayama K, Ogawa S, Nagata N, Miyamura T, Takeda N. |
| Title | Expression of sapovirus virus-like particles in mammalian cells. |
| Journal | Arch Virol |
| Abstract |
Sapovirus (SaV) is an etiological agent of acute gastroenteritis in human and swine. SaV can be divided into five genogroups, GI to GV. Virus-like particles (VLPs) morphologically similar to native SaV have been expressed for GI, GII, GIII and GV strains in insect cells, although only low expression levels were observed for GII strains. In this study, we report the successful expression of SaV GII VLPs using cultured mammalian COS-7 and 293T cells. Our results demonstrated that this mammalian expression system was able to express and form SaV VLPs. |
| Volume | 151(2) |
| Pages | 399-404 |
| Published | 2006-2-1 |
| DOI | 10.1007/s00705-005-0613-y |
| PMID | 16132181 |
| MeSH | Animals Cell Line Chlorocebus aethiops Gene Expression Regulation, Viral* Humans Sapovirus / classification Sapovirus / genetics* Sapovirus / growth & development* Sapovirus / metabolism Virus Replication* |
| IF | 2.243 |
| Times Cited | 12 |
| WOS Category | VIROLOGY |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | Patent(IFI CLAIMS) |
| Total number of mentions | 10 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Human and Animal Cells | COS-7(RCB0539) 293T(RCB2202) |