RRC ID 42678
Author Ohguchi K, Akao Y, Nozawa Y.
Title Stimulation of melanogenesis by the citrus flavonoid naringenin in mouse B16 melanoma cells.
Journal Biosci Biotechnol Biochem
Abstract Naringenin is a naturally occurring citrus flavanone. In this study, we examined the effect of naringenin on melanogenesis in mouse B16 melanoma cells. Melanin contents and tyrosinase activities were strongly increased by naringenin. Naringenin was found to cause marked increases in the expression levels of melanogenic enzymes.
Volume 70(6)
Pages 1499-501
Published 2006-6-1
DOI 10.1271/bbb.50635
PII JST.JSTAGE/bbb/50635
PMID 16794334
MeSH Animals Cell Line, Tumor Citrus / chemistry* Flavanones / chemistry Flavanones / pharmacology* Gene Expression Regulation, Neoplastic Melanins / metabolism* Melanoma / metabolism* Melanoma / pathology Mice Molecular Structure
IF 1.516
Times Cited 35
WOS Category FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY
Resource
Human and Animal Cells