RRC ID 4276
Author Paschinger K, Gutternigg M, Rendić D, Wilson IB.
Title The N-glycosylation pattern of Caenorhabditis elegans.
Journal Carbohydr. Res.
Abstract Determining the exact nature of N-glycosylation in Caenorhabditis elegans, a nematode worm and genetic model organism, has proved to have been an unexpected challenge in recent years; a wide range of modifications of its N-linked oligosaccharides have been proposed on the basis of structural and genomic analysis. Particularly mass spectrometric studies by a number of groups, as well as the characterisation of recombinant enzymes, have highlighted those aspects of N-glycosylation that are conserved in animals, those which are seemingly unique to this species and those which are shared with parasitic nematodes. These data, of importance for therapeutic developments, are reviewed.
Volume 343(12)
Pages 2041-9
Published 2008-8-11
DOI 10.1016/j.carres.2007.12.018
PII S0008-6215(07)00545-9
PMID 18226806
MeSH Animals Caenorhabditis elegans / genetics Caenorhabditis elegans / metabolism* Carbohydrate Sequence Glycomics Glycosylation
IF 1.873
Times Cited 54
WOS Category CHEMISTRY, ORGANIC CHEMISTRY, APPLIED BIOCHEMISTRY & MOLECULAR BIOLOGY
Resource
C.elegans tm1078 tm2350