RRC ID 4276
著者 Paschinger K, Gutternigg M, Rendić D, Wilson IB.
タイトル The N-glycosylation pattern of Caenorhabditis elegans.
ジャーナル Carbohydr Res
Abstract Determining the exact nature of N-glycosylation in Caenorhabditis elegans, a nematode worm and genetic model organism, has proved to have been an unexpected challenge in recent years; a wide range of modifications of its N-linked oligosaccharides have been proposed on the basis of structural and genomic analysis. Particularly mass spectrometric studies by a number of groups, as well as the characterisation of recombinant enzymes, have highlighted those aspects of N-glycosylation that are conserved in animals, those which are seemingly unique to this species and those which are shared with parasitic nematodes. These data, of importance for therapeutic developments, are reviewed.
巻・号 343(12)
ページ 2041-9
公開日 2008-8-11
DOI 10.1016/j.carres.2007.12.018
PII S0008-6215(07)00545-9
PMID 18226806
MeSH Animals Caenorhabditis elegans / genetics Caenorhabditis elegans / metabolism* Carbohydrate Sequence Glycomics Glycosylation
IF 1.841
引用数 65
WOS 分野 CHEMISTRY, ORGANIC CHEMISTRY, APPLIED BIOCHEMISTRY & MOLECULAR BIOLOGY
リソース情報
線虫 tm1078 tm2350