論文 - 詳細
RRC ID | 43505 |
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著者 | Oike H, Kobori M. |
タイトル | Resveratrol regulates circadian clock genes in Rat-1 fibroblast cells. |
ジャーナル | Biosci Biotechnol Biochem |
Abstract |
Circadian clocks, especially peripheral clocks, can be strongly entrained by daily feedings, but few papers have reported the effects of food components on circadian rhythm. The effects of resveratrol, a natural polyphenol, on circadian clocks of Rat-1 cells were analyzed. A dose of 100 muM resveratrol, which did not show cytotoxicity, regulated the expression of clock genes Per1, Per2, and Bmal1. |
巻・号 | 72(11) |
ページ | 3038-40 |
公開日 | 2008-11-1 |
DOI | 10.1271/bbb.80426 |
PII | JST.JSTAGE/bbb/80426 |
PMID | 18997419 |
MeSH | Animals Cell Line Cell Survival / drug effects Circadian Rhythm / drug effects* Circadian Rhythm / genetics* Fibroblasts / cytology Fibroblasts / drug effects Fibroblasts / metabolism Gene Expression Regulation / drug effects* Humans Rats Resveratrol Stilbenes / pharmacology* Time Factors |
IF | 1.516 |
引用数 | 29 |
WOS 分野 | FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY |
リソース情報 | |
ヒト・動物細胞 |