RRC ID 43750
Author Shimizu M, Kobayashi Y, Mizoguchi T, Nakamura H, Kawahara I, Narita N, Usui Y, Aoki K, Hara K, Haniu H, Ogihara N, Ishigaki N, Nakamura K, Kato H, Kawakubo M, Dohi Y, Taruta S, Kim YA, Endo M, Ozawa H, Udagawa N, Takahashi N, Saito N.
Title Carbon nanotubes induce bone calcification by bidirectional interaction with osteoblasts.
Journal Adv Mater
Abstract Multi-walled carbon nanotubes (MWCNTs) promote calcification during hydroxyapatite (HA) formation by osteoblasts. Primary cultured osteoblasts are incubated with MWCNTs or carbon black. After culture for 3 weeks, the degree of calcification is very high in the 50 μg mL(-1) MWCNT group. Transmission electron microscopy shows needle-like crystals around the MWCNTs, and diffraction patterns reveal that the peak of the crystals almost coincides with the known peak of HA.
Volume 24(16)
Pages 2176-85
Published 2012-4-24
DOI 10.1002/adma.201103832
PMID 22447724
MeSH Animals Bone and Bones / cytology* Bone and Bones / drug effects Bone and Bones / physiology* Calcification, Physiologic / drug effects* Cell Differentiation / drug effects Cell Proliferation / drug effects Humans Male Mice NIH 3T3 Cells Nanotubes, Carbon* Osteoblasts / cytology Osteoblasts / drug effects*
IF 25.809
Times Cited 43
WOS Category PHYSICS, APPLIED PHYSICS, CONDENSED MATTER MATERIALS SCIENCE, MULTIDISCIPLINARY CHEMISTRY, PHYSICAL NANOSCIENCE & NANOTECHNOLOGY CHEMISTRY, MULTIDISCIPLINARY
Resource
Human and Animal Cells