論文 - 詳細
| RRC ID | 43750 |
|---|---|
| 著者 | Shimizu M, Kobayashi Y, Mizoguchi T, Nakamura H, Kawahara I, Narita N, Usui Y, Aoki K, Hara K, Haniu H, Ogihara N, Ishigaki N, Nakamura K, Kato H, Kawakubo M, Dohi Y, Taruta S, Kim YA, Endo M, Ozawa H, Udagawa N, Takahashi N, Saito N. |
| タイトル | Carbon nanotubes induce bone calcification by bidirectional interaction with osteoblasts. |
| ジャーナル | Adv Mater |
| Abstract |
Multi-walled carbon nanotubes (MWCNTs) promote calcification during hydroxyapatite (HA) formation by osteoblasts. Primary cultured osteoblasts are incubated with MWCNTs or carbon black. After culture for 3 weeks, the degree of calcification is very high in the 50 μg mL(-1) MWCNT group. Transmission electron microscopy shows needle-like crystals around the MWCNTs, and diffraction patterns reveal that the peak of the crystals almost coincides with the known peak of HA. |
| 巻・号 | 24(16) |
| ページ | 2176-85 |
| 公開日 | 2012-4-24 |
| DOI | 10.1002/adma.201103832 |
| PMID | 22447724 |
| MeSH | Animals Bone and Bones / cytology* Bone and Bones / drug effects Bone and Bones / physiology* Calcification, Physiologic / drug effects* Cell Differentiation / drug effects Cell Proliferation / drug effects Humans Male Mice NIH 3T3 Cells Nanotubes, Carbon* Osteoblasts / cytology Osteoblasts / drug effects* |
| IF | 27.398 |
| 引用数 | 43 |
| WOS 分野 | PHYSICS, APPLIED PHYSICS, CONDENSED MATTER MATERIALS SCIENCE, MULTIDISCIPLINARY CHEMISTRY, PHYSICAL NANOSCIENCE & NANOTECHNOLOGY CHEMISTRY, MULTIDISCIPLINARY |
| リソース情報 | |
| ヒト・動物細胞 | MC3T3-E1(RCB1126) NIH3T3 ST2(RCB0224) |