| RRC ID |
43998
|
| 著者 |
Harimoto K, Yoshida Y, Yoshihara K, Nagaoka N, Matsumoto T, Tagawa Y.
|
| タイトル |
Osteoblast compatibility of materials depends on serum protein absorbability in osteogenesis.
|
| ジャーナル |
Dent Mater J
|
| Abstract |
Titanium has an osseointegrative property, while hydroxyapatite has an osteoconductive property. It remains a matter of controversy among researchers whether hydroxyapatite has higher osteoblast compatibility than titanium. Here, we compared the activities between osteoblasts cultured on titanium and those cultured on hydroxyapatite. An osteoblast-like cell line, MC3T3-E1, was cultured on machined titanium, evaporated titanium, and hydroxyapatite disks to compare the affinity of osteoblasts to each of these materials. The adhesion and proliferation of MC3T3-E1 cells were higher on hydroxyapatite disks than on the other disks. Osteoblast differentiation was not affected by the nature of disks investigated, but calcium was more easily deposited on the hydroxyapatite disks. The amount of absorbed serum proteins detected on hydroxyapatite was greater than that on titanium. In conclusion, our results indicate hydroxyapatite is a more suitable material for osteoblast growth than titanium because of its higher absorption of serum proteins.
|
| 巻・号 |
31(4)
|
| ページ |
674-80
|
| 公開日 |
2012-1-1
|
| DOI |
10.4012/dmj.2012-075
|
| PII |
DN/JST.JSTAGE/dmj/2012-075
|
| PMID |
22864224
|
| MeSH |
3T3 Cells
Absorption
Animals
Biocompatible Materials* / metabolism
Blood Proteins / metabolism*
Cell Adhesion
Cell Culture Techniques*
Cell Differentiation
Cell Proliferation
Durapatite* / chemistry
Durapatite* / metabolism
Mice
Osseointegration / physiology*
Osteoblasts / physiology*
Titanium* / chemistry
Titanium* / metabolism
|
| IF |
1.359
|
| 引用数 |
3
|
|
WOS 分野
|
DENTISTRY, ORAL SURGERY & MEDICINE
MATERIALS SCIENCE, BIOMATERIALS
|
| リソース情報 |
| ヒト・動物細胞 |
MC3T3-E1(RCB1126) |
