論文 - 詳細
| RRC ID | 44085 |
|---|---|
| 著者 | Hermawan I, de Voogd NJ, Tanaka J. |
| タイトル | An acetylenic alkaloid from the calcareous sponge Leucetta sp. |
| ジャーナル | Mar Drugs |
| Abstract |
A new acetylenic alkaloid was isolated from the sponge Leucetta sp. The structure was established by analyzing spectroscopic data. The alkaloid showed cytotoxicity IC₅₀ 2.5 μg/mL against NBT-T2 cells. |
| 巻・号 | 9(3) |
| ページ | 382-6 |
| 公開日 | 2011-3-21 |
| DOI | 10.3390/md9030382 |
| PMID | 21556167 |
| PMC | PMC3083658 |
| MeSH | Acetylene / administration & dosage Acetylene / isolation & purification Acetylene / pharmacology* Alkaloids / administration & dosage Alkaloids / isolation & purification Alkaloids / pharmacology* Animals Antineoplastic Agents / administration & dosage Antineoplastic Agents / isolation & purification Antineoplastic Agents / pharmacology Cell Line, Tumor Inhibitory Concentration 50 Porifera / chemistry* Rats Spectrum Analysis |
| 引用数 | 42 |
| WOS 分野 | CELL BIOLOGY |
| リソース情報 | |
| ヒト・動物細胞 | NBT-T2(RCB1370) |