RRC ID 44278
著者 Yoneyama Y, Matsuno T, Hashimoto Y, Satoh T.
タイトル In vitro evaluation of H2O2 hydrothermal treatment of aged titanium surface to enhance biofunctional activity.
ジャーナル Dent Mater J
Abstract Surface modification of titanium has been extensively investigated in implant science and technology in an effort to improve its osteoconductivity. The rate of protein adsorption on titanium surfaces is known to vary depending on the chemistry, structure, morphology, and titanium-specific biological aging of the surface. It is thus desirable to modify smooth titanium surfaces of miniimplants used as orthodontic anchors immediately prior to use. In this study, we have developed a simple surface modification of titanium alloy that improves its biofunctional activity. The surface of a Ti-6Al-4V disk was modified by applying 3% H(2)O(2) hydrothermal treatment using an autoclave. A nanostructured porous network TiO(2) was observed on the treated surface. Treated surfaces exhibited higher hydrophilicity, protein adsorption, and cell proliferation than untreated surfaces. 3% H(2)O(2) hydrothermal treatment is thought to provide biofunctional activity for aged titanium surface.
巻・号 32(1)
ページ 115-21
公開日 2013-1-1
DOI 10.4012/dmj.2012-087
PII DN/JST.JSTAGE/dmj/2012-087
PMID 23370879
MeSH 3T3 Cells Animals Biocompatible Materials / chemistry Cell Adhesion / drug effects* Cell Culture Techniques Cell Proliferation / drug effects* Dental Alloys / chemistry* Hydrogen Peroxide / pharmacology* Materials Testing Mice Microscopy, Electron, Scanning Osteoblasts / cytology Osteoblasts / drug effects* Osteoblasts / metabolism Photoelectron Spectroscopy Surface Properties Titanium / chemistry*
IF 1.359
引用数 12
WOS 分野 DENTISTRY, ORAL SURGERY & MEDICINE MATERIALS SCIENCE, BIOMATERIALS
リソース情報
ヒト・動物細胞 MC3T3-E1(RCB1126)