RRC ID |
44278
|
著者 |
Yoneyama Y, Matsuno T, Hashimoto Y, Satoh T.
|
タイトル |
In vitro evaluation of H2O2 hydrothermal treatment of aged titanium surface to enhance biofunctional activity.
|
ジャーナル |
Dent Mater J
|
Abstract |
Surface modification of titanium has been extensively investigated in implant science and technology in an effort to improve its osteoconductivity. The rate of protein adsorption on titanium surfaces is known to vary depending on the chemistry, structure, morphology, and titanium-specific biological aging of the surface. It is thus desirable to modify smooth titanium surfaces of miniimplants used as orthodontic anchors immediately prior to use. In this study, we have developed a simple surface modification of titanium alloy that improves its biofunctional activity. The surface of a Ti-6Al-4V disk was modified by applying 3% H(2)O(2) hydrothermal treatment using an autoclave. A nanostructured porous network TiO(2) was observed on the treated surface. Treated surfaces exhibited higher hydrophilicity, protein adsorption, and cell proliferation than untreated surfaces. 3% H(2)O(2) hydrothermal treatment is thought to provide biofunctional activity for aged titanium surface.
|
巻・号 |
32(1)
|
ページ |
115-21
|
公開日 |
2013-1-1
|
DOI |
10.4012/dmj.2012-087
|
PII |
DN/JST.JSTAGE/dmj/2012-087
|
PMID |
23370879
|
MeSH |
3T3 Cells
Animals
Biocompatible Materials / chemistry
Cell Adhesion / drug effects*
Cell Culture Techniques
Cell Proliferation / drug effects*
Dental Alloys / chemistry*
Hydrogen Peroxide / pharmacology*
Materials Testing
Mice
Microscopy, Electron, Scanning
Osteoblasts / cytology
Osteoblasts / drug effects*
Osteoblasts / metabolism
Photoelectron Spectroscopy
Surface Properties
Titanium / chemistry*
|
IF |
1.359
|
引用数 |
12
|
WOS 分野
|
DENTISTRY, ORAL SURGERY & MEDICINE
MATERIALS SCIENCE, BIOMATERIALS
|
リソース情報 |
ヒト・動物細胞 |
MC3T3-E1(RCB1126) |