RRC ID 44411
著者 Zheng Z, Ren L, Zhai Z, Wang Y, Hang F.
タイトル Surface modification on polyethylene terephthalate films with 2-methacryloyloxyethyl phosphorylcholine.
ジャーナル Mater Sci Eng C Mater Biol Appl
Abstract In this study, the surface of polyethylene terephthalate (PET) was modified to improve the protein and cell adhesion behavior with low temperature ammonia plasma treatment followed by 2-methacryloyloxyethyl phosphorylcholine (MPC) grafting. The x-ray photoelectron spectroscopy (XPS) results showed that the -COO(-), -N-C=O and -P-O-H groups were successfully incorporated onto the sample surface after MPC grafting. Furthermore, formation of new bonds, -N= and N-H on the sample surface grafted with MPC was recorded by Fourier transform infrared spectroscopy (FTIR). A large number of spherical particles at submicron to nanometer scale were also observed on the surface by atomic force microscopy (AFM). The cell adhesion experiments on PET film surfaces were evaluated and the highly hydrophilic surfaces could not promote cell adhesion and spreading. All results achieved in this study have clearly indicated that the method combining low temperature ammonia plasma treatment and MPC grafting is an effective way of producing a suitably hydrophilic PET surface with the capability of weakening the protein adsorption greatly.
巻・号 33(5)
ページ 3041-6
公開日 2013-7-1
DOI 10.1016/j.msec.2013.03.036
PII S0928-4931(13)00198-7
PMID 23623130
MeSH Cell Adhesion Methacrylates / chemistry* Microscopy, Atomic Force Phosphorylcholine / analogs & derivatives* Phosphorylcholine / chemistry Photoelectron Spectroscopy Polyethylene Terephthalates / chemistry* Spectroscopy, Fourier Transform Infrared Surface Properties
IF 5.88
引用数 15
WOS 分野 MATERIALS SCIENCE, BIOMATERIALS
リソース情報
ヒト・動物細胞 ATDC5(RCB0565)