論文 - 詳細
| RRC ID | 44683 |
|---|---|
| 著者 | Shibata M, Kashiwazaki S, Saito TK. |
| タイトル | Photodynamic cell membrane perforation for intracellular electrodes. |
| ジャーナル | Annu Int Conf IEEE Eng Med Biol Soc |
| Abstract |
We report a new aspect of rapid (<10 seconds) light-induced cell membrane perforation for intracellular electrode by Hematoporphyrin (HP), which is an original photosensitizer for photodynamic therapy concept. A microelectrode insertion process to cell could be improved by pinpoint use of the photosensitizing effect to degenerate cell membranes prior to insertion. According to the concept, simple electrode coating with photosensitizer will enable intracellular electrode array for neural engineering. |
| 巻・号 | 2013 |
| ページ | 807-10 |
| 公開日 | 2013-1-1 |
| DOI | 10.1109/EMBC.2013.6609623 |
| PMID | 24109810 |
| MeSH | Animals Cell Membrane / drug effects* Cell Membrane / radiation effects Electricity Electrodes Electrophysiological Phenomena / drug effects Electrophysiological Phenomena / radiation effects Hematoporphyrins / pharmacology* Intracellular Space / drug effects* Intracellular Space / radiation effects* Microinjections PC12 Cells Photochemotherapy* Rats Signal Processing, Computer-Assisted |
| IF | 3.15 |
| 引用数 | 5 |
| WOS 分野 | ONCOLOGY |
| リソース情報 | |
| ヒト・動物細胞 | PC-12(RCB0009) |