論文 - 詳細
| RRC ID | 44775 |
|---|---|
| 著者 | Hayashi K, Pack CG, Sato MK, Mouri K, Kaizu K, Takahashi K, Okada Y. |
| タイトル | Viscosity and drag force involved in organelle transport: investigation of the fluctuation dissipation theorem. |
| ジャーナル | Eur Phys J E Soft Matter |
| Abstract |
We observed the motion of an organelle transported by motor proteins in cells using fluorescence microscopy. Particularly, among organelles, the mitochondria in PC12 cells were studied. A mitochondrion was dragged at a constant speed for several seconds without pausing. We investigated the fluctuation dissipation theorem for this constant drag motion by comparing it with the motion of Brownian beads that were incorporated into the cells by an electroporation method. We estimated the viscosity value inside cells from the diffusion coefficients of the beads. Then the viscosity value obtained by using the beads was found to be slightly lower than that obtained from the diffusion coefficient for the organelle motion via the Einstein relation. This discrepancy indicates the violation of the Einstein relation for the organelle motion. |
| 巻・号 | 36(12) |
| ページ | 136 |
| 公開日 | 2013-12-1 |
| DOI | 10.1140/epje/i2013-13136-6 |
| PMID | 24297312 |
| MeSH | Animals Facilitated Diffusion* Mitochondria / metabolism* Models, Biological Motion PC12 Cells Rats Viscosity |
| IF | 1.812 |
| 引用数 | 10 |
| WOS 分野 | PHYSICS, APPLIED MATERIALS SCIENCE, MULTIDISCIPLINARY POLYMER SCIENCE CHEMISTRY, PHYSICAL |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 12 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| ヒト・動物細胞 | |