RRC ID 4498
Author Kaino T, Takagi H.
Title Proline as a stress protectant in the yeast Saccharomyces cerevisiae: effects of trehalose and PRO1 gene expression on stress tolerance.
Journal Biosci. Biotechnol. Biochem.
Abstract Proline is considered to be a stress protectant in the yeast Saccharomyces cerevisiae, as is trehalose. In this study, we constructed yeast strains that accumulate proline but not trehalose and that increase proline levels in response to stress. Our results suggest that proline does not complement the function of trehalose, and that moderate expression of the PRO1 gene encoding gamma-glutamyl kinase is important to stress tolerance of yeast cells.
Volume 73(9)
Pages 2131-5
Published 2009-9
DOI 10.1271/bbb.90299
PII JST.JSTAGE/bbb/90299
PMID 19734662
MeSH Adaptation, Physiological / genetics* Base Sequence DNA Primers Gene Expression* Genes, Fungal* Phosphotransferases (Carboxyl Group Acceptor) / genetics* Polymerase Chain Reaction Proline / physiology* Saccharomyces cerevisiae / genetics Saccharomyces cerevisiae / physiology* Stress, Physiological* Trehalose / pharmacology*
IF 1.255
Times Cited 7
WOS Category FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY
Resource
Yeast ?