RRC ID 4498
著者 Kaino T, Takagi H.
タイトル Proline as a stress protectant in the yeast Saccharomyces cerevisiae: effects of trehalose and PRO1 gene expression on stress tolerance.
ジャーナル Biosci Biotechnol Biochem
Abstract Proline is considered to be a stress protectant in the yeast Saccharomyces cerevisiae, as is trehalose. In this study, we constructed yeast strains that accumulate proline but not trehalose and that increase proline levels in response to stress. Our results suggest that proline does not complement the function of trehalose, and that moderate expression of the PRO1 gene encoding gamma-glutamyl kinase is important to stress tolerance of yeast cells.
巻・号 73(9)
ページ 2131-5
公開日 2009-9-1
DOI 10.1271/bbb.90299
PII JST.JSTAGE/bbb/90299
PMID 19734662
MeSH Adaptation, Physiological / genetics* Base Sequence DNA Primers Gene Expression* Genes, Fungal* Phosphotransferases (Carboxyl Group Acceptor) / genetics* Polymerase Chain Reaction Proline / physiology* Saccharomyces cerevisiae / genetics Saccharomyces cerevisiae / physiology* Stress, Physiological* Trehalose / pharmacology*
IF 1.516
引用数 10
WOS 分野 FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY
リソース情報
酵母