Reference - Detail
| RRC ID | 4499 |
|---|---|
| Author | Ookubo A, Hirasawa T, Yoshikawa K, Nagahisa K, Furusawa C, Shimizu H. |
| Title | Improvement of L-lactate production by CYB2 gene disruption in a recombinant Saccharomyces cerevisiae strain under low pH condition. |
| Journal | Biosci Biotechnol Biochem |
| Abstract |
Using a DNA microarray, we found that expression of the genes related to lactate metabolism was upregulated in a lactate-producing recombinant Saccharomyces cerevisiae strain. Disruption of the CYB2 gene encoding L-lactate dehydrogenase improved the L-lactate production by S. cerevisiae under low pH condition. |
| Volume | 72(11) |
| Pages | 3063-6 |
| Published | 2008-11-1 |
| DOI | 10.1271/bbb.80493 |
| PII | JST.JSTAGE/bbb/80493 |
| PMID | 18997405 |
| MeSH | Genetic Engineering* Humans Hydrogen-Ion Concentration L-Lactate Dehydrogenase / genetics* L-Lactate Dehydrogenase / metabolism Lactic Acid / biosynthesis* Saccharomyces cerevisiae / genetics* Saccharomyces cerevisiae / metabolism* |
| IF | 1.516 |
| Times Cited | 11 |
| WOS Category | FOOD SCIENCE & TECHNOLOGY CHEMISTRY, APPLIED BIOTECHNOLOGY & APPLIED MICROBIOLOGY BIOCHEMISTRY & MOLECULAR BIOLOGY |
| Resource | |
| Yeast | BYP1463(=pUG6) |