論文 - 詳細
| RRC ID | 45184 |
|---|---|
| 著者 | Sakai S, Khanmohammadi M, Khoshfetrat AB, Taya M. |
| タイトル | Horseradish peroxidase-catalyzed formation of hydrogels from chitosan and poly(vinyl alcohol) derivatives both possessing phenolic hydroxyl groups. |
| ジャーナル | Carbohydr Polym |
| Abstract |
Horseradish peroxidase-catalyzed cross-linking was applied to prepare hydrogels from aqueous solutions containing chitosan and poly(vinyl alcohol) derivatives both possessing phenolic hydroxyl groups (denoted as Ph-chitosan and Ph-PVA, respectively). Comparing the hydrogels prepared from the solution of 1.0% (w/v) Ph-chitosan and 3.0% (w/v) Ph-PVA and that of 3.0% (w/v) Ph-chitosan and 1.0% (w/v) Ph-PVA, the gelation time of the former hydrogel was 47 s, while was 10s longer than that of the latter one. The breaking point for the former hydrogel under stretching (114% strain) was approximately twice larger than that for the latter one. The swelling ratio of the former hydrogel in saline was about half of the latter one. Fibroblastic cells did not adhere on the former hydrogel but adhered and spread on the latter one. The growth of Escherichia coli cells was fully suppressed on the latter hydrogel during 48 h cultivation. |
| 巻・号 | 111 |
| ページ | 404-9 |
| 公開日 | 2014-10-13 |
| DOI | 10.1016/j.carbpol.2014.05.010 |
| PII | S0144-8617(14)00476-7 |
| PMID | 25037368 |
| MeSH | Anti-Bacterial Agents / chemistry* Anti-Bacterial Agents / metabolism Anti-Bacterial Agents / pharmacology Biocompatible Materials / chemistry* Biocompatible Materials / metabolism Biocompatible Materials / pharmacology Chitosan / chemistry* Chitosan / metabolism Chitosan / pharmacology Escherichia coli / drug effects Escherichia coli Infections / prevention & control Horseradish Peroxidase / metabolism Humans Hydrogels / chemistry* Hydrogels / metabolism Hydrogels / pharmacology Phenols / chemistry Phenols / metabolism Phenols / pharmacology Polyvinyl Alcohol / analogs & derivatives* Polyvinyl Alcohol / metabolism Polyvinyl Alcohol / pharmacology |
| IF | 7.182 |
| 引用数 | 25 |
| WOS 分野 | POLYMER SCIENCE CHEMISTRY, ORGANIC CHEMISTRY, APPLIED |
| リソース情報 | |
| ヒト・動物細胞 | 10T1/2(RCB0247) |