Reference - Detail
RRC ID | 45236 |
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Author | Tai A, Aburada M, Ito H. |
Title | A simple efficient synthesis and biological evaluation of 3-O-ethylascorbic acid. |
Journal | Biosci Biotechnol Biochem |
Abstract |
A single-step synthesis of 3-O-ethyl-l-ascorbic acid was performed without the induction of protecting groups. Sodium l-ascorbate reacted with ethyl bromide in DMSO to give 3-O-ethylascorbic acid in a yield of 51.0%. 3-O-Ethylascorbic acid enhanced dibutyryl cyclic AMP-induced neurite outgrowth in PC12 cells. |
Volume | 78(12) |
Pages | 1984-7 |
Published | 2014-1-1 |
DOI | 10.1080/09168451.2014.946396 |
PMID | 25127395 |
MeSH | Animals Ascorbic Acid / analogs & derivatives* Ascorbic Acid / chemical synthesis Ascorbic Acid / chemistry Ascorbic Acid / pharmacology Bromides / chemistry Bucladesine / metabolism Calcium / metabolism Cell Survival / drug effects Neurites / drug effects* PC12 Cells Rats |
IF | 1.516 |
Times Cited | 1 |
WOS Category | FOOD SCIENCE & TECHNOLOGY BIOTECHNOLOGY & APPLIED MICROBIOLOGY CHEMISTRY, APPLIED BIOCHEMISTRY & MOLECULAR BIOLOGY |
Resource | |
Human and Animal Cells | PC-12(RCB0009) |