| RRC ID |
45264
|
| Author |
Shimada M, Ozawa M, Iwamoto K, Fukuyama Y, Kishida A, Ohsaki A.
|
| Title |
A lanostane triterpenoid and three cholestane sterols from Tilia kiusiana.
|
| Journal |
Chem Pharm Bull (Tokyo)
|
| Abstract |
Kiusianins A-D (1-4) were isolated from the leaves of a Japanese endemic plant, Tilia kiusiana, together with 14 known compounds. The structures of a new lanostane-type triterpenoid 1 and three new cholestane-type sterols 2-4 were elucidated by spectroscopic methods, including two dimensional (2D) NMR. All the compounds isolated were evaluated for their cytotoxicity against two human cancer cell lines, HeLa and HL-60.
|
| Volume |
62(9)
|
| Pages |
937-41
|
| Published |
2014-1-1
|
| DOI |
10.1248/cpb.c14-00200
|
| PII |
DN/JST.JSTAGE/cpb/c14-00200
|
| PMID |
25177022
|
| MeSH |
Cell Line, Tumor
Cholestanes / isolation & purification*
Humans
Magnetic Resonance Spectroscopy
Sterols / isolation & purification*
Tilia / chemistry*
Triterpenes / isolation & purification*
|
| IF |
1.416
|
| Times Cited |
9
|
|
WOS Category
|
PHARMACOLOGY & PHARMACY
CHEMISTRY, MULTIDISCIPLINARY
CHEMISTRY, MEDICINAL
|
| Resource |
| Human and Animal Cells |
HeLa
HL-60 |