| RRC ID |
45278
|
| Author |
Nishikawa H, Noshita T, Tai A, Ouchi H, Okamoto T, Saito A, Yamada T, Iomori A, Ishimata N.
|
| Title |
Syntheses and biological activities of the proposed structure of apteniol A and its derivatives.
|
| Journal |
Biosci Biotechnol Biochem
|
| Abstract |
We describe the syntheses of the proposed structure of diphenyl ether oxyneolignan, apteniol A and its derivatives. The diphenyl ether moiety of proposed apteniol A was formed via Ullmann ether synthesis, but the spectral data of the synthesized apteniol A did not agree with that in previous studies. The dimethyl ester derivative of the proposed apteniol A was found to enhance neurite outgrowth in PC12 cells and inhibit antigen-induced degranulation in RBL-2H3 cells.
|
| Volume |
78(9)
|
| Pages |
1485-9
|
| Published |
2014-1-1
|
| DOI |
10.1080/09168451.2014.930322
|
| PMID |
25209495
|
| MeSH |
Animals
Cell Degranulation / drug effects
Cell Degranulation / immunology
Ether / chemical synthesis
Ether / chemistry*
Ether / pharmacology
Lignans / chemical synthesis
Lignans / chemistry*
Lignans / pharmacology
Mast Cells / drug effects
Neurites / drug effects*
Neurogenesis / drug effects
PC12 Cells
Rats
|
| IF |
1.516
|
| Times Cited |
3
|
|
WOS Category
|
FOOD SCIENCE & TECHNOLOGY
BIOTECHNOLOGY & APPLIED MICROBIOLOGY
CHEMISTRY, APPLIED
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
| Resource |
| Human and Animal Cells |
PC-12(RCB0009) |
