論文 - 詳細
| RRC ID | 46217 |
|---|---|
| 著者 | Turner EA, Kroeger GL, Arnold MC, Thornton BL, Di Giulio RT, Meyer JN. |
| タイトル | Assessing different mechanisms of toxicity in mountaintop removal/valley fill coal mining-affected watershed samples using Caenorhabditis elegans. |
| ジャーナル | PLoS One |
| Abstract |
Mountaintop removal-valley fill coal mining has been associated with a variety of impacts on ecosystem and human health, in particular reductions in the biodiversity of receiving streams. However, effluents emerging from valley fills contain a complex mixture of chemicals including metals, metalloids, and salts, and it is not clear which of these are the most important drivers of toxicity. We found that streamwater and sediment samples collected from mine-impacted streams of the Upper Mud River in West Virginia inhibited the growth of the nematode Caenorhabditis elegans. Next, we took advantage of genetic and transgenic tools available in this model organism to test the hypotheses that the toxicity could be attributed to metals, selenium, oxidative stress, or osmotic stress. Our results indicate that in general, the toxicity of streamwater to C. elegans was attributable to osmotic stress, while the toxicity of sediments resulted mostly from metals or metalloids. |
| 巻・号 | 8(9) |
| ページ | e75329 |
| 公開日 | 2013-1-1 |
| DOI | 10.1371/journal.pone.0075329 |
| PII | PONE-D-13-19476 |
| PMID | 24066176 |
| PMC | PMC3774817 |
| MeSH | Animals Caenorhabditis elegans / drug effects Coal Mining* Ecosystem Environmental Monitoring / methods* Geologic Sediments Water Pollutants, Chemical / toxicity |
| IF | 2.74 |
| 引用数 | 17 |
| WOS 分野 | ENVIRONMENTAL SCIENCES |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 6 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 線虫 | tm1748 |