Reference - Detail
| RRC ID | 46734 |
|---|---|
| Author | Martin R, Entchev EV, Kurzchalia TV, Knölker HJ. |
| Title | Steroid hormones controlling the life cycle of the nematode Caenorhabditis elegans: stereoselective synthesis and biology. |
| Journal | Org Biomol Chem |
| Abstract |
Cholesterol-derived hormones, the dafachronic acids, play a major role in controlling the life cycle and initiating dauer larva formation of the nematode Caenorhabditis elegans. This Perspective describes recent progress in the synthesis of these steroid hormones and their biological function. |
| Volume | 8(4) |
| Pages | 739-50 |
| Published | 2010-2-21 |
| DOI | 10.1039/b918488k |
| PMID | 20135027 |
| MeSH | Animals Caenorhabditis elegans / physiology* Caenorhabditis elegans Proteins / biosynthesis Caenorhabditis elegans Proteins / physiology* Cholesterol / pharmacology Gene Expression Regulation, Developmental / drug effects Gene Expression Regulation, Developmental / physiology Genes, Helminth Hormones / pharmacology* Larva / drug effects Larva / physiology Life Cycle Stages / drug effects* Life Cycle Stages / physiology Longevity / drug effects Signal Transduction / physiology Stereoisomerism Steroids / pharmacology* |
| IF | 3.412 |
| Times Cited | 18 |
| WOS Category | CHEMISTRY, ORGANIC |
| Resource | |
| C.elegans | tm1781 |