| RRC ID |
46812
|
| 著者 |
Mukai Y, Nureki S, Hata M, Shigenaga T, Tokimatsu I, Miyazaki E, Kadota J, Yarita K, Kamei K.
|
| タイトル |
Exophiala dermatitidis pneumonia successfully treated with long-term itraconazole therapy.
|
| ジャーナル |
J Infect Chemother
|
| Abstract |
Exophiala dermatitidis pneumonia is extremely rare. Here we report a case of E. dermatitidis pneumonia successfully treated with long-term itraconazole therapy. A 63-year-old woman without a remarkable medical history developed a dry and chest pain. Chest radiographs revealed consolidation in the middle lobe of the lung. Cytologic examination by bronchoscopy showed filamentous fungi and E. dermatitidis was detected in the bronchoalveolar lavage fluid. After 5 months of itraconazole therapy, her symptoms improved and the area of consolidation diminished. Two weeks after discontinuing the itraconazole therapy, the area of consolidation reappeared. Itraconazole therapy was restarted and continued for 7 months. The abnormal shadow observed on the chest X-ray gradually diminished. Over a 27-month follow-up with periodic examination, there was no relapse and the patient had a favorable clinical course.
|
| 巻・号 |
20(7)
|
| ページ |
446-9
|
| 公開日 |
2014-7-1
|
| DOI |
10.1016/j.jiac.2014.02.006
|
| PII |
S1341-321X(14)00115-9
|
| PMID |
24767462
|
| MeSH |
Antifungal Agents / therapeutic use
Exophiala / isolation & purification*
Female
Humans
Itraconazole / therapeutic use*
Middle Aged
Phaeohyphomycosis / drug therapy*
Phaeohyphomycosis / microbiology
Pneumonia / drug therapy*
Pneumonia / microbiology
|
| IF |
1.722
|
| 引用数 |
3
|
|
WOS 分野
|
INFECTIOUS DISEASES
PHARMACOLOGY & PHARMACY
|
| リソース情報 |
| 病原微生物 |
NA |
