Reference - Detail
| RRC ID | 46824 |
|---|---|
| Author | Tanaka N, Tsuji E, Sakai K, Gonoi T, Kobayashi J. |
| Title | Hikiokoshins A-I, diterpenes from the leaves of Isodon japonicus. |
| Journal | Phytochemistry |
| Abstract |
Diterpenes, hikiokoshins A-I, and twelve known diterpenes were isolated from the leaves of Isodon japonicus (Burm. f.) H. Hara (Lamiaceae). The hikiokoshins A-I possess various skeletons such as ternifonane {hikiokoshin A}, ent-6,7:8,15-diseco-6,8-cyclokauran-7,20-olide {hikiokoshin B}, ent-6,7-secokauran-7,20-olide {hikiokoshin C}, and ent-7,20-epoxykaurane {hikiokoshins D-I}. Their structures were elucidated on the basis of spectroscopic analysis. Antimicrobial activities of hikiokoshins A and B were evaluated. |
| Volume | 102 |
| Pages | 205-10 |
| Published | 2014-6-1 |
| DOI | 10.1016/j.phytochem.2014.03.001 |
| PII | S0031-9422(14)00104-6 |
| PMID | 24702849 |
| MeSH | Animals Anti-Bacterial Agents / chemistry Anti-Bacterial Agents / isolation & purification Anti-Bacterial Agents / pharmacology* Antifungal Agents / chemistry Antifungal Agents / isolation & purification Antifungal Agents / pharmacology* Bacteria / drug effects* Cell Line, Tumor Diterpenes / chemistry Diterpenes / isolation & purification Diterpenes / pharmacology* Fungi / drug effects* Humans Isodon / chemistry* Mice Molecular Conformation Plant Leaves / chemistry Stereoisomerism |
| IF | 3.044 |
| Times Cited | 9 |
| WOS Category | PLANT SCIENCES BIOCHEMISTRY & MOLECULAR BIOLOGY |
| Resource | |
| Pathogenic microorganisms | |