| RRC ID |
46856
|
| Author |
Kubota T, Kamijyo Y, Takahashi-Nakaguchi A, Fromont J, Gonoi T, Kobayashi J.
|
| Title |
Zamamiphidin A, a new manzamine related alkaloid from an Okinawan marine sponge Amphimedon sp.
|
| Journal |
Org Lett
|
| Abstract |
A manzamine related alkaloid, zamamiphidin A (1), consisting of a new heptacyclic ring system has been isolated from an Okinawan marine sponge Amphimedon sp. The structure of 1 including the relative stereochemistry was elucidated on the basis of the spectroscopic data. Compound 1 showed antibacterial activity against Staphylococcus aureus (MIC, 32 μg/mL).
|
| Volume |
15(3)
|
| Pages |
610-2
|
| Published |
2013-2-1
|
| DOI |
10.1021/ol3034274
|
| PMID |
23343122
|
| MeSH |
Alkaloids / chemistry
Alkaloids / isolation & purification*
Alkaloids / pharmacology
Animals
Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / isolation & purification*
Anti-Bacterial Agents / pharmacology
Carbazoles
Drug Screening Assays, Antitumor
Humans
Japan
Microbial Sensitivity Tests
Porifera / chemistry*
Staphylococcus aureus / drug effects
|
| IF |
6.091
|
| Times Cited |
18
|
|
WOS Category
|
CHEMISTRY, ORGANIC
|
| Resource |
| Pathogenic microorganisms |
NA |
