論文 - 詳細
| RRC ID | 46865 |
|---|---|
| 著者 | Tanaka N, Asai M, Takahashi-Nakaguchi A, Gonoi T, Fromont J, Kobayashi J. |
| タイトル | Manzamenone O, new trimeric fatty acid derivative from a marine sponge Plakortis sp. |
| ジャーナル | Org Lett |
| Abstract |
A new structurally unique trimeric fatty acid derivative, manzamenone O (1), was isolated from a marine sponge Plakortis sp. Manzamenone O (1) has a novel skeleton consisting of C-C bonded octahydroindenone and dioxabicyclo[3.3.0]octane moieties and three long aliphatic chains. The structure of 1 was elucidated on the basis of spectroscopic data and conformational analysis. Manzamenone O (1) exhibited antimicrobial activity against Micrococcus luteus, Aspergillis niger, and Trichophyton mentagrophytes. |
| 巻・号 | 15(10) |
| ページ | 2518-21 |
| 公開日 | 2013-5-17 |
| DOI | 10.1021/ol4009975 |
| PMID | 23651077 |
| MeSH | Animals Anti-Infective Agents / chemistry* Anti-Infective Agents / isolation & purification Anti-Infective Agents / pharmacology* Fatty Acids / chemistry* Fatty Acids / isolation & purification Indenes / chemistry* Indenes / isolation & purification Indenes / pharmacology* Magnetic Resonance Spectroscopy Molecular Structure Plakortis / chemistry* Polyketides / chemistry* Polyketides / isolation & purification Polyketides / pharmacology* |
| IF | 6.091 |
| 引用数 | 12 |
| WOS 分野 | CHEMISTRY, ORGANIC |
| リソース情報 | |
| 病原微生物 | NA |