Reference - Detail
| RRC ID | 46877 |
|---|---|
| Author | Kobayashi N, Sueoka-Aragane N, Naganobu N, Umeguchi H, Kusaba K, Nagasawa Z, Yazawa K, Gonoi T, Kimura S, Hayashi S. |
| Title | Disseminated Nocardiosis caused by Nocardia concava with acute respiratory failure and central nervous system involvement treated with linezolid. |
| Journal | Intern Med |
| Abstract |
Nocardia concava was identified as a new species in 2005; however, the clinical manifestations of Nocardia concava infection have yet to be clarified. We herein present the case of an immunosuppressed patient who developed disseminated nocardiosis caused by N. concava with multiple abscesses in the lungs, cutis, subcutaneous tissue, skeletal muscles and kidneys accompanied by central nervous system involvement, including meningitis and ventriculitis. The patient was cured with appropriate treatment including linezolid after testing for susceptibility. Linezolid should be considered as an alternative agent for treating disseminated nocardiosis because of its effective distribution to multiple sites. |
| Volume | 51(23) |
| Pages | 3281-5 |
| Published | 2012-1-1 |
| DOI | 10.2169/internalmedicine.51.7733 |
| PII | DN/JST.JSTAGE/internalmedicine/51.7733 |
| PMID | 23207125 |
| MeSH | Acetamides / therapeutic use* Acute Disease Aged Anti-Bacterial Agents / therapeutic use* Central Nervous System Diseases / diagnosis Central Nervous System Diseases / drug therapy* Central Nervous System Diseases / microbiology Humans Immunocompromised Host Linezolid Male Microbial Sensitivity Tests Minocycline / therapeutic use Nocardia / classification Nocardia / drug effects Nocardia / genetics Nocardia Infections / diagnosis Nocardia Infections / drug therapy* Nocardia Infections / microbiology Oxazolidinones / therapeutic use* Respiratory Insufficiency / drug therapy* Respiratory Insufficiency / microbiology Trimethoprim, Sulfamethoxazole Drug Combination / therapeutic use |
| IF | 0.956 |
| Times Cited | 3 |
| Resource | |
| Pathogenic microorganisms | IFM 0354 IFM 0576 |