RRC ID 46881
著者 Li G, He D, Qian Y, Guan B, Gao S, Cui Y, Yokoyama K, Wang L.
タイトル Fungus-mediated green synthesis of silver nanoparticles using Aspergillus terreus.
ジャーナル Int J Mol Sci
Abstract The biosynthesis of nanoparticles has received increasing attention due to the growing need to develop safe, cost-effective and environmentally friendly technologies for nano-materials synthesis. In this report, silver nanoparticles (AgNPs) were synthesized using a reduction of aqueous Ag(+) ion with the culture supernatants of Aspergillus terreus. The reaction occurred at ambient temperature and in a few hours. The bioreduction of AgNPs was monitored by ultraviolet-visible spectroscopy, and the AgNPs obtained were characterized by transmission electron microscopy and X-ray diffraction. The synthesized AgNPs were polydispersed spherical particles ranging in size from 1 to 20 nm and stabilized in the solution. Reduced nicotinamide adenine dinucleotide (NADH) was found to be an important reducing agent for the biosynthesis, and the formation of AgNPs might be an enzyme-mediated extracellular reaction process. Furthermore, the antimicrobial potential of AgNPs was systematically evaluated. The synthesized AgNPs could efficiently inhibit various pathogenic organisms, including bacteria and fungi. The current research opens a new avenue for the green synthesis of nano-materials.
巻・号 13(1)
ページ 466-76
公開日 2012-1-1
DOI 10.3390/ijms13010466
PII ijms13010466
PMID 22312264
PMC PMC3269698
MeSH Anti-Infective Agents / chemistry Anti-Infective Agents / metabolism* Anti-Infective Agents / pharmacology Aspergillus / metabolism* Bacteria / drug effects Biomass Fungi / drug effects Green Chemistry Technology Metal Nanoparticles / chemistry* Metal Nanoparticles / toxicity NAD / chemistry Particle Size Silver / chemistry*
IF 4.556
引用数 179
WOS 分野 BIOCHEMISTRY & MOLECULAR BIOLOGY CHEMISTRY, MULTIDISCIPLINARY
リソース情報
病原微生物 IFM 40808 IFM 55648