| RRC ID |
46884
|
| Author |
Mori T, Nakamura Y, Kato J, Sugita K, Murata M, Kamei K, Okamoto S.
|
| Title |
Fungemia due to Rhodotorula mucilaginosa after allogeneic hematopoietic stem cell transplantation.
|
| Journal |
Transpl Infect Dis
|
| Abstract |
Rhodotorula species have been increasingly recognized as emerging pathogens, particularly in immunocompromised patients. We herein report on a patient with myelodysplastic syndrome who developed fungemia due to Rhodotorula mucilaginosa after allogeneic hematopoietic stem cell transplantation (HSCT) from an unrelated donor. He developed severe acute graft-versus-host disease requiring high-dose steroids, and had serially been administered fluconazole and micafungin for the prophylaxis of fungal infection. Although several cases of Rhodotorula infection after HSCT have been reported, all of them were recipients of autologous HSCT, not allogeneic HSCT. A review of all the reported cases of Rhodotorula infection after HSCT revealed that all patients had received fluconazole or echinocandins before the onset of infection. The findings suggest that Rhodotorula species could be causative yeasts, particularly in patients receiving fluconazole or echinocandins, both of which are inactive against the species.
|
| Volume |
14(1)
|
| Pages |
91-4
|
| Published |
2012-2-1
|
| DOI |
10.1111/j.1399-3062.2011.00647.x
|
| PMID |
21535337
|
| MeSH |
Amphotericin B / therapeutic use
Antifungal Agents / therapeutic use
Fungemia / drug therapy
Fungemia / microbiology*
Graft vs Host Disease / etiology
Hematopoietic Stem Cell Transplantation / adverse effects*
Humans
Male
Middle Aged
Mycoses / drug therapy
Mycoses / microbiology*
Myelodysplastic Syndromes / therapy
Rhodotorula / classification
Rhodotorula / genetics
Rhodotorula / isolation & purification*
Transplantation, Homologous / adverse effects
Unrelated Donors
|
| IF |
2.071
|
| Times Cited |
18
|
|
WOS Category
|
TRANSPLANTATION
INFECTIOUS DISEASES
IMMUNOLOGY
|
| Resource |
| Pathogenic microorganisms |
|
