論文 - 詳細
| RRC ID | 46918 |
|---|---|
| 著者 | Kon Y, Kubota T, Shibazaki A, Gonoi T, Kobayashi J. |
| タイトル | Ceratinadins A-C, new bromotyrosine alkaloids from an Okinawan marine sponge Pseudoceratina sp. |
| ジャーナル | Bioorg Med Chem Lett |
| Abstract |
Three new bromotyrosine alkaloids, ceratinadins A-C (1-3), were isolated from an Okinawan marine sponge Pseudoceratina sp. and the structures of 1-3 were elucidated on the basis of spectroscopic data. Ceratinadin A (1) was a novel bromotyrosine alkaloid possessing an N-imidazolyl-quinolinone moiety. Ceratinadins A (1) and B (2) showed antifungal activity. |
| 巻・号 | 20(15) |
| ページ | 4569-72 |
| 公開日 | 2010-8-1 |
| DOI | 10.1016/j.bmcl.2010.06.015 |
| PII | S0960-894X(10)00779-1 |
| PMID | 20584605 |
| MeSH | Alkaloids / chemistry* Alkaloids / isolation & purification Alkaloids / pharmacology Animals Antifungal Agents / chemistry* Antifungal Agents / isolation & purification Antifungal Agents / pharmacology Imidazoles / chemistry* Imidazoles / isolation & purification Imidazoles / pharmacology Magnetic Resonance Spectroscopy Molecular Conformation Porifera / chemistry* Quinolines / chemistry* Quinolines / isolation & purification Quinolines / pharmacology Tyrosine / analogs & derivatives* Tyrosine / chemistry |
| IF | 2.572 |
| 引用数 | 28 |
| WOS 分野 | CHEMISTRY, MEDICINAL CHEMISTRY, ORGANIC |
| リソース情報 | |
| 病原微生物 | NA |