RRC ID 46938
著者 Takahashi Y, Kubota T, Shibazaki A, Gonoi T, Fromont J, Kobayashi J.
タイトル Nakijinamines C-E, new heteroaromatic alkaloids from the sponge Suberites species.
ジャーナル Org Lett
Abstract Three new heteroaromatic alkaloids, nakijinamines C-E (1-3), which are a hybrid of the aaptamine-type and bromoindole alkaloids possessing a taurine- or histidine-derived residue, have been isolated from an Okinawan marine sponge Suberites species. The structures of 1-3 were elucidated on the basis of spectroscopic data and chemical conversions. Nakijinamines C (1) and E (3) are the first natural products possessing a 1H-oxazolo[4',5':4,5]benzo[1,2,3-de][1,6]naphthyridine ring system.
巻・号 13(12)
ページ 3016-9
公開日 2011-6-17
DOI 10.1021/ol2008473
PMID 21574567
MeSH Animals Aspergillus niger / drug effects Drug Screening Assays, Antitumor Hydrocarbons, Brominated / chemistry Hydrocarbons, Brominated / isolation & purification* Indole Alkaloids / chemistry Indole Alkaloids / isolation & purification* Leukemia P388 Microbial Sensitivity Tests Molecular Structure Nuclear Magnetic Resonance, Biomolecular Suberites / chemistry*
IF 6.091
引用数 27
WOS 分野 CHEMISTRY, ORGANIC
リソース情報
病原微生物 NA