論文 - 詳細
RRC ID | 46938 |
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著者 | Takahashi Y, Kubota T, Shibazaki A, Gonoi T, Fromont J, Kobayashi J. |
タイトル | Nakijinamines C-E, new heteroaromatic alkaloids from the sponge Suberites species. |
ジャーナル | Org Lett |
Abstract |
Three new heteroaromatic alkaloids, nakijinamines C-E (1-3), which are a hybrid of the aaptamine-type and bromoindole alkaloids possessing a taurine- or histidine-derived residue, have been isolated from an Okinawan marine sponge Suberites species. The structures of 1-3 were elucidated on the basis of spectroscopic data and chemical conversions. Nakijinamines C (1) and E (3) are the first natural products possessing a 1H-oxazolo[4',5':4,5]benzo[1,2,3-de][1,6]naphthyridine ring system. |
巻・号 | 13(12) |
ページ | 3016-9 |
公開日 | 2011-6-17 |
DOI | 10.1021/ol2008473 |
PMID | 21574567 |
MeSH | Animals Aspergillus niger / drug effects Drug Screening Assays, Antitumor Hydrocarbons, Brominated / chemistry Hydrocarbons, Brominated / isolation & purification* Indole Alkaloids / chemistry Indole Alkaloids / isolation & purification* Leukemia P388 Microbial Sensitivity Tests Molecular Structure Nuclear Magnetic Resonance, Biomolecular Suberites / chemistry* |
IF | 6.091 |
引用数 | 27 |
WOS 分野 | CHEMISTRY, ORGANIC |
リソース情報 | |
病原微生物 | NA |