RRC ID |
46953
|
著者 |
Nishikata N, Nakamori K, Sueyoshi M, Takahashi H, Yuji H, Sano A.
|
タイトル |
[Evaluation of antifungal effects of a traditional medicine containing 17 components on Trichophyton verrucosum and Malassezia pachydermatis by microdilution].
|
ジャーナル |
Med Mycol J
|
Abstract |
The minimum inhibitory concentration(MIC)of a traditional medicine containing 17 components against 9 strains of Trichophyton verrucosum and 13 strains of Malassezia pachydermatis was determined using a method recommended by the Clinical and Laboratory Standards Institute(CLSI). We also measured the MIC of each of the 17 components using the same method, and identified the main antifungal components.In order to evaluate MIC as a parameter of the antifungal effects using the microdilution method, we prepared 10% working solutions from 10% (w/v)medicines. The geometric mean MIC of the medicinal extract against T. verrucosum was 2.51%, and that against M. pachydermatis was 2.25%. The components that exhibited antifungal effects were Rheum palmatum, Glycyrrhiza uralensis, Magnolia obovata, Phellodendron amurense, and Geranium thunbergii.
|
巻・号 |
52(3)
|
ページ |
213-21
|
公開日 |
2011-1-1
|
DOI |
10.3314/mmj.52.213
|
PII |
JST.JSTAGE/mmj/52.213
|
PMID |
21891983
|
MeSH |
Animals
Drug Resistance, Fungal
Drugs, Chinese Herbal / chemistry*
Drugs, Chinese Herbal / pharmacology*
Malassezia / drug effects*
Microbial Sensitivity Tests / methods*
Trichophyton / drug effects*
|
リソース情報 |
病原微生物 |
IFM 5798
IFM 40205
IFM 40212
IFM 40214
IFM 54301
IFM 55518
IFM 56537
IFM 56813
IFM 57574
IFM 57575
IFM 58256
IFM 58543
IFM 58544
IFM 58793
IFM 58794
IFM 58795
IFM 58796
IFM 58797
IFM 58798
IFM 58799
IFM 58800
IFM 58801
IFM 58802 |