RRC ID |
47024
|
Author |
Xi L, Sun J, Lu C, Liu H, Xie Z, Fukushima K, Takizawa K, Najafzadeh MJ, De Hoog GS.
|
Title |
Molecular diversity of Fonsecaea (Chaetothyriales) causing chromoblastomycosis in southern China.
|
Journal |
Med Mycol
|
Abstract |
Chromoblastomycosis is a chronic, cutaneous and subcutaneous infection caused by members of the order Chaetothyriales and commonly found in China. Among the etiologic agents, members of the genus Cladophialophora are predominant in northern China. Alternatively, Fonsecaea spp. are particularly common in southern China. However, the identification of Fonsecaea isolates recovered in China is difficult due to the fact that different species lack distinctive morphological characters. Therefore, the identification of 24 Fonsecaea isolates from symptomatic patients were re-evaluated by using morphology, ITS rDNA sequence diversity and partly through the use of randomly amplified polymorphic DNA (RAPD) typing. Twenty strains, including a morphological mutant were found to be Fonsecaea monophora, while four strains corresponded to F. pedrosoi. We have demonstrated that Fonsecaea monophora is the predominant etiologic agent of chromoblastomycosis in southern China and populations showed marked geographic structuring.
|
Volume |
47(1)
|
Pages |
27-33
|
Published |
2009-2-1
|
DOI |
10.1080/13693780802468209
|
PII |
904846923
|
PMID |
18951291
|
MeSH |
Ascomycota / classification*
Ascomycota / genetics
Ascomycota / physiology
Ascomycota / ultrastructure
China / epidemiology
Chromoblastomycosis / epidemiology*
Chromoblastomycosis / microbiology
Chromoblastomycosis / pathology
DNA, Fungal / analysis
DNA, Ribosomal
DNA, Ribosomal Spacer / analysis
Genetic Variation*
Humans
Mycological Typing Techniques
Phylogeny
Random Amplified Polymorphic DNA Technique
Sequence Analysis, DNA
Species Specificity
|
IF |
2.822
|
Times Cited |
53
|
WOS Category
|
VETERINARY SCIENCES
MYCOLOGY
INFECTIOUS DISEASES
|
Resource |
Pathogenic microorganisms |
IFM 4886
IFM 41704
IFM 41705
IFM 41931
IFM 46410 |