Reference - Detail
| RRC ID | 47044 |
|---|---|
| Author | Ono M, Kobayashi Y, Shibata T, Maruyama D, Kim SW, Watanabe T, Mikami Y, Tobinai K. |
| Title | Nocardia exalbida brain abscess in a patient with follicular lymphoma. |
| Journal | Int J Hematol |
| Abstract |
Nocardial brain abscess is a rare but severe complication in patients with malignancy. Nocardia exalbida was isolated in Japan and characterized within the genus Nocardia. We present the first report of N. exalbida brain abscess in a 63-year-old male patient with follicular lymphoma. He developed abnormal neurological findings during follicular lymphoma treatment, brain CT revealed ring-enhancing, multiloculated lesions, and N. exalbida was detected by aspiration of the lesion. He was successfully treated with trimethoprime-sulfamethoxazole (TMP-SMX) and meropenem without craniotomy or repeat aspirations. It should be noted that such an infection can occur in patients treated with conventional chemotherapy against malignant lymphoma. |
| Volume | 88(1) |
| Pages | 95-100 |
| Published | 2008-7-1 |
| DOI | 10.1007/s12185-008-0099-y |
| PII | 10.1007/s12185-008-0099-y |
| PMID | 18498026 |
| MeSH | Anti-Bacterial Agents / administration & dosage* Antineoplastic Combined Chemotherapy Protocols / administration & dosage* Antineoplastic Combined Chemotherapy Protocols / adverse effects Brain Abscess / chemically induced Brain Abscess / drug therapy* Brain Abscess / microbiology Brain Abscess / pathology Cyclophosphamide / administration & dosage Cyclophosphamide / adverse effects Doxorubicin / administration & dosage Doxorubicin / adverse effects Humans Lymphoma, Follicular / drug therapy* Lymphoma, Follicular / microbiology Lymphoma, Follicular / pathology Male Middle Aged Nocardia* Nocardia Infections / chemically induced Nocardia Infections / drug therapy* Nocardia Infections / pathology Prednisone / administration & dosage Prednisone / adverse effects Remission Induction Vincristine / administration & dosage Vincristine / adverse effects |
| IF | 2.245 |
| Times Cited | 7 |
| WOS Category | HEMATOLOGY |
| Resource | |
| Pathogenic microorganisms | IFM 10794 |