RRC ID 47565
著者 Honma M, Tanaka K, Konno K, Tsuge K, Okuno T, Hashimoto M.
タイトル Termination of the structural confusion between plipastatin A1 and fengycin IX.
ジャーナル Bioorg Med Chem
Abstract Plipastatin A1 and fengycin IX were experimentally proven to be identical compounds, while these had been considered as diastereomers due to the permutation of the enantiomeric pair of Tyr in most papers. The (1)H NMR spectrum changed to become quite similar to that of plipastatin A1, when the sample which provided resembled spectrum of fengycin IX was treated with KOAc followed by LH-20 gel filtration. Our structural investigations disclosed that the structures of these molecules should be settled into that of plipastatin A1 by Umezawa (L-Tyr4 and D-Tyr10).
巻・号 20(12)
ページ 3793-8
公開日 2012-6-15
DOI 10.1016/j.bmc.2012.04.040
PII S0968-0896(12)00324-0
PMID 22609073
MeSH Bacillus subtilis / chemistry Bacillus subtilis / isolation & purification Fatty Acids / chemistry* Magnetic Resonance Spectroscopy Molecular Structure Oligopeptides / chemistry* Peptides, Cyclic / chemistry* Stereoisomerism
IF 3.073
引用数 15
WOS 分野 CHEMISTRY, MEDICINAL CHEMISTRY, ORGANIC BIOCHEMISTRY & MOLECULAR BIOLOGY
リソース情報
一般微生物 JCM 18293