論文 - 詳細
| RRC ID | 47630 |
|---|---|
| 著者 | Moriyoshi K, Masu M, Ishii T, Shigemoto R, Mizuno N, Nakanishi S. |
| タイトル | Molecular cloning and characterization of the rat NMDA receptor. |
| ジャーナル | Nature |
| Abstract |
A complementary DNA encoding the rat NMDA receptor has been cloned and characterized. The single protein encoded by the cDNA forms a receptor-channel complex that has electrophysiological and pharmacological properties characteristic of the NMDA receptor. This protein has a significant sequence similarity to the AMPA/kainate receptors and contains four putative transmembrane segments following a large extracellular domain. The NMDA receptor messenger RNA is expressed in neuronal cells throughout the brain regions, particularly in the hippocampus, cerebral cortex and cerebellum. |
| 巻・号 | 354(6348) |
| ページ | 31-7 |
| 公開日 | 1991-11-7 |
| DOI | 10.1038/354031a0 |
| PMID | 1834949 |
| MeSH | Amino Acid Sequence Animals Base Sequence Brain / metabolism* Cloning, Molecular Electrophysiology Ibotenic Acid / analogs & derivatives Ibotenic Acid / chemistry Kainic Acid / chemistry Molecular Sequence Data Molecular Structure RNA, Messenger / analysis Rats Receptors, N-Methyl-D-Aspartate / genetics* Xenopus / genetics alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid |
| IF | 42.779 |
| 引用数 | 1701 |
| WOS 分野 | BIOCHEMISTRY & MOLECULAR BIOLOGY |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | Patent(IFI CLAIMS) |
| 各媒体での言及数の合計 | 36 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 遺伝子材料 | pN 60 ( NR1 ) (RDB13202) |