| RRC ID |
47630
|
| 著者 |
Moriyoshi K, Masu M, Ishii T, Shigemoto R, Mizuno N, Nakanishi S.
|
| タイトル |
Molecular cloning and characterization of the rat NMDA receptor.
|
| ジャーナル |
Nature
|
| Abstract |
A complementary DNA encoding the rat NMDA receptor has been cloned and characterized. The single protein encoded by the cDNA forms a receptor-channel complex that has electrophysiological and pharmacological properties characteristic of the NMDA receptor. This protein has a significant sequence similarity to the AMPA/kainate receptors and contains four putative transmembrane segments following a large extracellular domain. The NMDA receptor messenger RNA is expressed in neuronal cells throughout the brain regions, particularly in the hippocampus, cerebral cortex and cerebellum.
|
| 巻・号 |
354(6348)
|
| ページ |
31-7
|
| 公開日 |
1991-11-7
|
| DOI |
10.1038/354031a0
|
| PMID |
1834949
|
| MeSH |
Amino Acid Sequence
Animals
Base Sequence
Brain / metabolism*
Cloning, Molecular
Electrophysiology
Ibotenic Acid / analogs & derivatives
Ibotenic Acid / chemistry
Kainic Acid / chemistry
Molecular Sequence Data
Molecular Structure
RNA, Messenger / analysis
Rats
Receptors, N-Methyl-D-Aspartate / genetics*
Xenopus / genetics
alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
|
| IF |
42.779
|
| 引用数 |
1701
|
|
WOS 分野
|
BIOCHEMISTRY & MOLECULAR BIOLOGY
|
| リソース情報 |
| 遺伝子材料 |
pN 60 ( NR1 ) (RDB13202) |
