Reference - Detail
| RRC ID | 48263 |
|---|---|
| Author | Sriswasdi S, Takashima M, Manabe R, Ohkuma M, Sugita T, Iwasaki W. |
| Title | Global deceleration of gene evolution following recent genome hybridizations in fungi. |
| Journal | Genome Res |
| Abstract |
Polyploidization events such as whole-genome duplication and inter-species hybridization are major evolutionary forces that shape genomes. Although long-term effects of polyploidization have been well-characterized, early molecular evolutionary consequences of polyploidization remain largely unexplored. Here, we report the discovery of two recent and independent genome hybridizations within a single clade of a fungal genus, Trichosporon Comparative genomic analyses revealed that redundant genes are experiencing decelerations, not accelerations, of evolutionary rates. We identified a relationship between gene conversion and decelerated evolution suggesting that gene conversion may improve the genome stability of young hybrids by restricting gene functional divergences. Furthermore, we detected large-scale gene losses from transcriptional and translational machineries that indicate a global compensatory mechanism against increased gene dosages. Overall, our findings illustrate counteracting mechanisms during an early phase of post-genome hybridization and fill a critical gap in existing theories on genome evolution. |
| Volume | 26(8) |
| Pages | 1081-90 |
| Published | 2016-8-1 |
| DOI | 10.1101/gr.205948.116 |
| PII | gr.205948.116 |
| PMID | 27440871 |
| PMC | PMC4971771 |
| MeSH | Deceleration* Evolution, Molecular* Gene Conversion Genome, Fungal / genetics* Hybridization, Genetic Phylogeny Polyploidy Trichosporon / genetics* |
| IF | 11.093 |
| Times Cited | 7 |
| WOS Category | BIOTECHNOLOGY & APPLIED MICROBIOLOGY GENETICS & HEREDITY BIOCHEMISTRY & MOLECULAR BIOLOGY |
| Altmetric score |
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| The most frequently cited source | X(Twitter) |
| Total number of mentions | 20 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| General Microbes | JCM 2938 JCM 9940 JCM 2941 JCM 9195 |