| RRC ID |
49589
|
| Author |
Cinege G, Zsámboki J, Vidal-Quadras M, Uv A, Csordás G, Honti V, Gábor E, Hegedűs Z, Varga GIB, Kovács AL, Juhász G, Williams MJ, Andó I, Kurucz É.
|
| Title |
Genes encoding cuticular proteins are components of the Nimrod gene cluster in Drosophila.
|
| Journal |
Insect Biochem Mol Biol
|
| Abstract |
The Nimrod gene cluster, located on the second chromosome of Drosophila melanogaster, is the largest synthenic unit of the Drosophila genome. Nimrod genes show blood cell specific expression and code for phagocytosis receptors that play a major role in fruit fly innate immune functions. We previously identified three homologous genes (vajk-1, vajk-2 and vajk-3) located within the Nimrod cluster, which are unrelated to the Nimrod genes, but are homologous to a fourth gene (vajk-4) located outside the cluster. Here we show that, unlike the Nimrod candidates, the Vajk proteins are expressed in cuticular structures of the late embryo and the late pupa, indicating that they contribute to cuticular barrier functions.
|
| Volume |
87
|
| Pages |
45-54
|
| Published |
2017-8-1
|
| DOI |
10.1016/j.ibmb.2017.06.006
|
| PII |
S0965-1748(17)30082-6
|
| PMID |
28633893
|
| MeSH |
Animals
Drosophila Proteins / genetics*
Drosophila melanogaster / genetics*
Drosophila melanogaster / growth & development
Embryo, Nonmammalian
Genes, Insect*
Multigene Family*
Pupa / genetics
Pupa / growth & development
|
| IF |
3.827
|
| Times Cited |
4
|
| Resource |
| Drosophila |
|
