Reference - Detail
| RRC ID | 49634 |
|---|---|
| Author | Matuo Y, Izumi Y, Furusawa Y, Shimizu K. |
| Title | Biological effects of carbon ion beams with various LETs on budding yeast Saccharomyces cerevisiae. |
| Journal | Mutat Res |
| Abstract |
It has been established that irradiation with higher linear energy transfer (LET) increases lethality and mutagenicity more than that with lower LET. However, the characteristics specific to carbon ion beam have not yet been elucidated. Yeast cells were irradiated with carbon ions with an LET of 13 or 50keV/μm, and cell survival and mutation frequency were analyzed. The results, combined with our previous findings for ions with an LET of 107keV/μm, demonstrated that, in conjunction with an increase in LET, cell survival decreased, while mutation frequency increased. This indicates that a carbon ion beam with a higher LET is more mutagenic than one with a lower LET. |
| Volume | 810 |
| Pages | 45-51 |
| Published | 2018-7-1 |
| DOI | 10.1016/j.mrfmmm.2017.10.003 |
| PII | S0027-5107(17)30052-0 |
| PMID | 29146154 |
| MeSH | Carbon Cell Survival / radiation effects Dose-Response Relationship, Radiation Heavy Ion Radiotherapy* Heavy Ions Linear Energy Transfer* Mutagenesis / radiation effects* Mutation Rate* Saccharomyces cerevisiae / radiation effects* |
| IF | 2.463 |
| Times Cited | 4 |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | Policy sources |
| Total number of mentions | 5 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Yeast | BY19656 BY19654 |