論文 - 詳細
| RRC ID | 50399 |
|---|---|
| 著者 | Shimogori T, Abe A, Go Y, Hashikawa T, Kishi N, Kikuchi SS, Kita Y, Niimi K, Nishibe H, Okuno M, Saga K, Sakurai M, Sato M, Serizawa T, Suzuki S, Takahashi E, Tanaka M, Tatsumoto S, Toki M, U M, Wang Y, Windak KJ, Yamagishi H, Yamashita K, Yoda T, Yoshida AC, Yoshida C, Yoshimoto T, Okano H. |
| タイトル | Digital gene atlas of neonate common marmoset brain. |
| ジャーナル | Neurosci Res |
| Abstract |
Interest in the common marmoset (Callithrix jacchus) as a primate model animal has grown recently, in part due to the successful demonstration of transgenic marmosets. However, there is some debate as to the suitability of marmosets, compared to more widely used animal models, such as the macaque monkey and mouse. Especially, the usage of marmoset for animal models of human cognition and mental disorders, is still yet to be fully explored. To examine the prospects of the marmoset model for neuroscience research, the Marmoset Gene Atlas (https://gene-atlas.bminds.brain.riken.jp/) provides a whole brain gene expression atlas in the common marmoset. We employ in situ hybridization (ISH) to systematically analyze gene expression in neonate marmoset brains, which allows us to compare expression with other model animals such as mouse. We anticipate that these data will provide sufficient information to develop tools that enable us to reveal marmoset brain structure, function, cellular and molecular organization for primate brain research. |
| 巻・号 | 128 |
| ページ | 1-13 |
| 公開日 | 2018-3-1 |
| DOI | 10.1016/j.neures.2017.10.009 |
| PII | S0168-0102(17)30587-4 |
| PMID | 29111135 |
| MeSH | Animals Animals, Genetically Modified Brain / metabolism* Callithrix / genetics* Cognition / drug effects* Disease Models, Animal Gene Expression* Macaca |
| IF | 2.645 |
| 引用数 | 4 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 5 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 遺伝子材料 | Common marmoset cDNA Clone MMTD (RDB19268). |