Reference - Detail
| RRC ID | 50565 |
|---|---|
| Author | Nishimura T, Yamada K, Fujimori C, Kikuchi M, Kawasaki T, Siegfried KR, Sakai N, Tanaka M. |
| Title | Germ cells in the teleost fish medaka have an inherent feminizing effect. |
| Journal | PLoS Genet |
| Abstract |
AUTHOR SUMMARY:Germ cells are the only cells that can transfer genetic materials to the next generation via the sperm or egg. However, recent analyses in teleosts revealed another essential role of germ cells: feminizing the gonads. In our study, medaka mutants in which gametogenesis was blocked at specific stages provides the novel view that the feminizing effect of germ cells occurs in parallel with other reproductive elements, such as meiosis, the sexual fate decision of germ cells, and gametogenesis. Germ cells in medaka may have a potential to feminize gonads at the moment they have developed. |
| Volume | 14(3) |
| Pages | e1007259 |
| Published | 2018-3-1 |
| DOI | 10.1371/journal.pgen.1007259 |
| PII | PGENETICS-D-17-01674 |
| PMID | 29596424 |
| PMC | PMC5875746 |
| MeSH | Animals Cell Lineage Female Feminization* Gametogenesis Germ Cells / cytology* Male Meiosis Oryzias / genetics* Sex Differentiation |
| IF | 5.175 |
| Times Cited | 8 |
| Altmetric score |
オルトメトリクス指標項目
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| The most frequently cited source | X(Twitter) |
| Total number of mentions | 1480 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Medaka | fosmid clone (GOLWFno462_j06) OK-Cab (MT830) |