論文 - 詳細
| RRC ID | 51467 |
|---|---|
| 著者 | Lee D, Yang H, Kim J, Brady S, Zdraljevic S, Zamanian M, Kim H, Paik YK, Kruglyak L, Andersen EC, Lee J. |
| タイトル | The genetic basis of natural variation in a phoretic behavior. |
| ジャーナル | Nat Commun |
| Abstract |
Phoresy is a widespread form of commensalism that facilitates dispersal of one species through an association with a more mobile second species. Dauer larvae of the nematode Caenorhabditis elegans exhibit a phoretic behavior called nictation, which could enable interactions with animals such as isopods or snails. Here, we show that natural C. elegans isolates differ in nictation. We use quantitative behavioral assays and linkage mapping to identify a genetic locus (nict-1) that mediates the phoretic interaction with terrestrial isopods. The nict-1 locus contains a Piwi-interacting small RNA (piRNA) cluster; we observe that the Piwi Argonaute PRG-1 is involved in the regulation of nictation. Additionally, this locus underlies a trade-off between offspring production and dispersal. Variation in the nict-1 locus contributes directly to differences in association between nematodes and terrestrial isopods in a laboratory assay. In summary, the piRNA-rich nict-1 locus could define a novel mechanism underlying phoretic interactions.Nematodes use a characteristic set of movements, called nictation, to hitchhike on more mobile animals. Here, Lee et al. identify a genetic locus in the nematode Caenorhabditis elegans that underlies nictation and contributes to successful hitchhiking, but at expense of reduced offspring production. |
| 巻・号 | 8(1) |
| ページ | 273 |
| 公開日 | 2017-8-17 |
| DOI | 10.1038/s41467-017-00386-x |
| PII | 10.1038/s41467-017-00386-x |
| PMID | 28819099 |
| PMC | PMC5561207 |
| MeSH | Animals Argonaute Proteins / genetics* Behavior, Animal* Caenorhabditis elegans / genetics* Caenorhabditis elegans Proteins / genetics* Chromosome Mapping Host-Parasite Interactions / genetics* Isopoda Larva / genetics Larva / physiology RNA, Small Interfering Symbiosis / genetics* |
| IF | 12.121 |
| 引用数 | 19 |
| オルトメトリクス指標 |
オルトメトリクス指標項目
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| 最多言及媒体 | X(Twitter) |
| 各媒体での言及数の合計 | 38 |
| 過去6か月間でのオルトメトリクス指標の変動値 | 0.0 |
| リソース情報 | |
| 線虫 | tm6979 |