Reference - Detail
| RRC ID | 51580 |
|---|---|
| Author | Ribeiro C, Correia V, Martins P, Gama FM, Lanceros-Mendez S. |
| Title | Proving the suitability of magnetoelectric stimuli for tissue engineering applications. |
| Journal | Colloids Surf B Biointerfaces |
| Abstract |
A novel approach for tissue engineering applications based on the use of magnetoelectric materials is presented. This work proves that magnetoelectric Terfenol-D/poly(vinylidene fluoride-co-trifluoroethylene) composites are able to provide mechanical and electrical stimuli to MC3T3-E1 pre-osteoblast cells and that those stimuli can be remotely triggered by an applied magnetic field. Cell proliferation is enhanced up to ≈ 25% when cells are cultured under mechanical (up to 110 ppm) and electrical stimulation (up to 0.115 mV), showing that magnetoelectric cell stimulation is a novel and suitable approach for tissue engineering allowing magnetic, mechanical and electrical stimuli. |
| Volume | 140 |
| Pages | 430-436 |
| Published | 2016-4-1 |
| DOI | 10.1016/j.colsurfb.2015.12.055 |
| PII | S0927-7765(15)30403-3 |
| PMID | 26797659 |
| MeSH | Alloys / chemistry Animals Cell Line Cell Proliferation* Dysprosium / chemistry Electric Stimulation Hydrocarbons, Fluorinated / chemistry Iron / chemistry Magnetic Fields* Membranes, Artificial Mice Microscopy, Fluorescence Osteoblasts / cytology* Reproducibility of Results Terbium / chemistry Tissue Engineering / instrumentation Tissue Engineering / methods* Tissue Scaffolds / chemistry Vinyl Compounds / chemistry |
| IF | 4.389 |
| Times Cited | 58 |
| Resource | |
| Human and Animal Cells | MC3T3-E1(RCB1126) |