Reference - Detail
| RRC ID | 51688 |
|---|---|
| Author | Yoshikawa M, Ouji Y. |
| Title | Induction of Inner Ear Hair Cells from Mouse Embryonic Stem Cells In Vitro. |
| Journal | Methods Mol Biol |
| Abstract |
Inner ear hair cells (HCs) function as the primary transducers for perception of sound and balance, while a defect in their formation or their loss results in sensory deficits. In mammals, once HCs are lost, they are not regenerated, and thus, various medical strategies have been proposed for their reproduction. Although embryonic stem (ES) cells are a promising source for cell therapy, little is known about efficient generation of hair cell-like cells (HCLs) from mouse ES cells. In the present protocol, we describe a simple method for obtaining ES-derived murine HCLs (HIST2 method). |
| Volume | 1516 |
| Pages | 257-267 |
| Published | 2016-1-1 |
| DOI | 10.1007/7651_2016_328 |
| PMID | 27032944 |
| MeSH | Animals Cell Culture Techniques / methods* Cell Differentiation / genetics* Hair Cells, Auditory, Inner / cytology* Mice Mouse Embryonic Stem Cells / cytology* Regeneration |
| Altmetric score |
オルトメトリクス指標項目
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| Total number of mentions | 0 |
| Altmetric score changes over past 6months | 0.0 |
| Resource | |
| Human and Animal Cells | ST2(RCB0224) |