RRC ID 51808
Author Koyama S, Narita E, Shimizu Y, Suzuki Y, Shiina T, Taki M, Shinohara N, Miyakoshi J.
Title Effects of Long-Term Exposure to 60 GHz Millimeter-Wavelength Radiation on the Genotoxicity and Heat Shock Protein (Hsp) Expression of Cells Derived from Human Eye.
Journal Int J Environ Res Public Health
Abstract Human corneal epithelial (HCE-T) and human lens epithelial (SRA01/04) cells derived from the human eye were exposed to 60 gigahertz (GHz) millimeter-wavelength radiation for 24 h. There was no statistically significant increase in the micronucleus (MN) frequency in cells exposed to 60 GHz millimeter-wavelength radiation at 1 mW/cm² compared with sham-exposed controls and incubator controls. The MN frequency of cells treated with bleomycin for 1 h provided positive controls. The comet assay, used to detect DNA strand breaks, and heat shock protein (Hsp) expression also showed no statistically significant effects of exposure. These results indicate that exposure to millimeter-wavelength radiation has no effect on genotoxicity in human eye cells.
Volume 13(8)
Published 2016-8-8
DOI 10.3390/ijerph13080802
PII ijerph13080802
PMID 27509516
PMC PMC4997488
MeSH Bleomycin Cell Line / radiation effects* Comet Assay DNA Damage / radiation effects* Eye* Heat-Shock Proteins / metabolism* Humans Lens, Crystalline Microwaves Radiation Exposure / adverse effects* Radio Waves / adverse effects*
IF 2.849
Times Cited 7
Resource
Human and Animal Cells HCE-T(RCB2280)