RRC ID 52621
Author Kuragano M, Uyeda TQP, Kamijo K, Murakami Y, Takahashi M.
Title Different contributions of nonmuscle myosin IIA and IIB to the organization of stress fiber subtypes in fibroblasts.
Journal Mol Biol Cell
Abstract We demonstrated that myosin IIA and IIB are essential for the formation of transverse arcs and ventral stress fibers, respectively. Furthermore, we illustrated the roles of both isoforms in lamellar flattening and also raised the possibility that actin filaments in ventral stress fibers are in a stretched conformation.
Volume 29(8)
Pages 911-922
Published 2018-4-15
DOI 10.1091/mbc.E17-04-0215
PII mbc.E17-04-0215
PMID 29467250
PMC PMC5896930
MeSH Cell Line Cell Movement* Cell Polarity Cell Shape Fibroblasts / cytology* Gene Knockdown Techniques Humans Nonmuscle Myosin Type IIA / metabolism* Nonmuscle Myosin Type IIB / metabolism* Phosphorylation Stress Fibers / metabolism*
IF 3.791
Times Cited 8
Resource
Human and Animal Cells MRC-5 SV1 TG1(RCB0207)